I only know of one person who followed some bad instructions on a Goldwing Forum and OD'ed his trike to the tune of $3000.00 worth of fuel system overhaul. This gentleman who is a 'Self-proclaimed' Goldwing Specialist/Guru (writer) posted that he (trike owner) must use the full can every other tankful three times and the problem would go away.So far I have not see it do any harm unless you go overboard with it.
If used sparingly it should not be a problem, We have had good luck with this product for years:s
I didn't know if they would get clogged
If you live in a state that measures CO & HC, you probably will have problems if the emission spec is low. Bikes may be exempt and have a allowable higher spec. I guess it all depends on the state.